https://www.biocinematics.com/dadreads daily 0.75 2018-06-24 https://www.biocinematics.com/blog daily 0.75 2019-11-27 https://www.biocinematics.com/blog/2019/11/26/diffusion-doesnt-tell-molecules-where-to-go monthly 0.5 2019-11-27 https://www.biocinematics.com/blog/2019/8/26/a-summer-move monthly 0.5 2019-08-27 https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1566866043716-LMND53022G9EJXBS1KQ0/2019Aug_bookshelf.jpg Blog - A Summer Move A good start. https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1566865938815-YFD8GLFVXNFSONMS73GV/2019Aug_moving_boxes.jpg Blog - A Summer Move How did all this fit in my last home office? https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1566865974313-BH3XBAOPQKR2ZTVHKYUG/2019Aug_computer_rebuild.jpg Blog - A Summer Move Putting my giant heatsink back in, along with the graphics cards and hard drives (shipped separately). https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1566866406283-N011UL0AV50W1MBCLGKE/2019Aug_wire_crt_tv.jpg Blog - A Summer Move It works! https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1566866302821-J8WT505PB6MQ2RP5PHQL/2019Aug_wire_crt.jpg Blog - A Summer Move I don’t know very much about electronics, but I had no qualms about sacrificing this old mini-USB cable. https://www.biocinematics.com/blog/2019/7/19/the-pinball-machine-of-science monthly 0.5 2019-07-20 https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1563633873446-WIESRIEKXNV1OZEF50JA/Pinball_model.png Blog - The Pinball Machine of Science https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1563634967503-952ED2TZIP3UNG56Z3RU/SPM_island_char_01.jpg Blog - The Pinball Machine of Science It’s a rock, despite my 2-year-old’s insistent assertions that it is in fact “a poop”. https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1563635402245-WT4FO924I9ZFT5LV1TLC/Island_refraction_Issue.png Blog - The Pinball Machine of Science A simple case (flat grey shaders) to simplify and isolate the problem - a very useful troubleshooting approach. https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1563632768246-7V5Q2LQY122Q3L4BGBKE/bad_bullet_rotation_2.gif Blog - The Pinball Machine of Science I never did figure out what was going on with this rolling, just tweaked settings until the problem was minimized. https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1563634498369-BCQSNXXCJ8D3MX43IQVX/Pinball_sim_helpers.png Blog - The Pinball Machine of Science Simple helper geometry shows me where the ball should go, and the numbered path shows where the ball is actually going. https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1563635195646-5IITSOR303O97R5CD13Q/Island_blocking_01.png Blog - The Pinball Machine of Science https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1563635369420-VOH2X0KA3Z3F0BPRBA2J/Island_LookDev_01.png Blog - The Pinball Machine of Science A little island in the sun https://www.biocinematics.com/blog/2019/6/25/are-you-really-a-carbon-based-life-form monthly 0.5 2019-09-27 https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1561496374336-COXBE0JU8OZZZLCV477R/PeriodicTable_04.png Blog - Are you really a carbon-based life-form? Oxygen comin’ atcha! https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1561496457417-EE2BSH9J7J43KAYJ7O47/ThinkingParticles_02.png Blog - Are you really a carbon-based life-form? The leaking was a lot worse in other iterations. https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1561496004066-XGHY0XWF0M3K3SH1WN56/PeriodicTable_02.png Blog - Are you really a carbon-based life-form? Computers start counting from zero. Adjust accordingly. https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1561496484353-5ATRQAZMFZH6U853FWMP/particle_intersection_rings.png Blog - Are you really a carbon-based life-form? Not quite right. https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1569614726145-7VWCTIKNTW39M4CIUG76/MBY001_thinker_thumbnail_plain_01.png Blog - Are you really a carbon-based life-form? https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1561496057702-9NKS1LVDDNMK9R57JS9Q/PeriodicTable_03.png Blog - Are you really a carbon-based life-form? If there are any typos, it’s wikipedia’s fault. https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1561496411693-Z6XULVSL006GMAWNBJZV/ThinkingParticles.png Blog - Are you really a carbon-based life-form? I’ve certainly felt like this before. https://www.biocinematics.com/blog/2019/4/29/osteocalcin-and-bone-mineral monthly 0.5 2019-04-29 https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1556562768652-9TG7QOYX72BQGHGPZB5E/Hydroxyapatite_single_cell.png Blog - Osteocalcin and Bone Mineral A single hydroxyapatite unit: Ca in green, PO4 in yellow/red, and OH in red/white https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1556562704769-APZAQ2YZATFE5ZM6Z4BI/Houdini_PDB_import_02.png Blog - Osteocalcin and Bone Mineral The green balls here are the important calcium ions. It didn’t take too many nodes to generate this, which is nice. https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1556562646820-9XRPK22KL415ZEBAUTN4/MTM904_Osteocalcin_v01.000.png Blog - Osteocalcin and Bone Mineral The glowing spheres are the calcium ions that osteocalcin is currently binding. https://www.biocinematics.com/blog/2019/3/29/backup-strategies monthly 0.5 2019-03-29 https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1553888008252-98LRJUHDD1DG9VEO72TF/2017-03-16+20.54.51.jpg Blog - Backup Strategies Fact: hard drives die. Fact: I am not a data recovery specialist. https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1553888523010-T7KTV6GLEJFT9E0D2WFF/LOTR_data_usage.jpg Blog - Backup Strategies That’s a hefty chunk for one trilogy… https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1553888698813-H36KUUF3OVTRANJY3AOJ/SJantzen-20141024_0001-20_BCM.jpg Blog - Backup Strategies This unit is about 6 years old and has been on almost 100% of that time. https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1553889325754-DZ9280I2R0ASY5XB0XTB/backblaze.jpg Blog - Backup Strategies Backblaze working round the clock https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1553888330628-F3FUX0POS2CN8D1RZWUG/SJantzen-20190112_11631_long.jpg Blog - Backup Strategies The legendary OS drive https://www.biocinematics.com/blog/2019/3/15/measles-virus-nucleocapsid monthly 0.5 2019-03-15 https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1552685250835-5GVTXTZZUXVQMS0QD96W/MTM903_lowres_unit.jpg Blog - Measles Virus Nucleocapsid Tip: After retopology of thin meshes, use the 3D Gizmo and ctrl+drag the yellow center to inflate the model closer to the original volume. https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1552685147212-J1NFU1SOB9UKQGBD1BTJ/MTM903_multiple_sims_02.jpg Blog - Measles Virus Nucleocapsid A bunch of simulations all stacked up https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1552685071857-EBGXZ3GCCZEXZQHCTC6S/MTM903_raw_pdb.jpg Blog - Measles Virus Nucleocapsid PDB 4UFT https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1552685559861-1OUK2UID1VHB8P4PSPQ0/MTM903_render_beautyRNA.jpg Blog - Measles Virus Nucleocapsid No connection to the Xbox Red Ring of Death https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1552685415628-CJXY39GJXHE62MZZ68BM/MTM903_lowres_RNA.jpg Blog - Measles Virus Nucleocapsid Turns out the RNA is all cytosine residues… so not perfectly accurate… shhh! https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1552685185972-RMRXJO1GJCDB8X63GI9G/MTM903_hires_unit.jpg Blog - Measles Virus Nucleocapsid 37 proteins and 222 RNA nucleotides https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1552684847731-AKMIUYCYBHX4LSC6PJ9U/Measles_virus_nucleocapsid_Biocinematics_1080.jpg Blog - Measles Virus Nucleocapsid Measles Virus Nucleocapsid - March Molecule of the Month https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1552685479944-CSPSCA5CME8W30TXUT91/MTM903_viewport_posed.jpg Blog - Measles Virus Nucleocapsid I believe this is approximately the correct full length of the measles genome, and yes it should fit inside a typical measles capsid. 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It was published as the cover of the Feb 2021 issue of Nature Chemistry. © 2020 David Leigh. https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1631561123260-BKSFQR5VP3FQN7V2SZPW/Biocinematics_molecular_pump_cover_2021.jpg Portfolio - Molecular Pump Cover https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1612931114295-NPUXOFNHUARSW3FBBS3V/Biocinematics_tying_different_knots_cover_2020.jpg Portfolio - Tying Different Knots from One Molecule A sculptural representation of a molecule being tied into two different knots, a trefoil knot on the left, and a five-crossing knot on the right. Metal binding sites are represented by copper and silvery regions. https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1612931799823-5PHACM1C2J229WC4D5GV/Biocinematics_stereosynthesis_robot_cover_2017.jpg Portfolio - Programmable Stereosynthesis Robot A molecular programmable robot arm can generate different stereoisomer products. The illustration highlights the mirrored nature of the different stereoisomer molecules being produced by the robotic arm. © 2017 David Leigh https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1612932621255-954YKNY2RC63PQ4GSWY7/Biocinematics_ribonucleotide_reductase_cover_2019.jpg Portfolio - Bacterial Ribonucleotide Reductase Bacterial ribonucleotide reductase, inactive form. The protein backbone atoms are colored black, while amino acid side-chains are colored based on category. https://images.squarespace-cdn.com/content/v1/561822e9e4b04b4330084b25/1612932109850-LQE7106J8SCECOS5PKDP/Biocinematics_8-19_knot_cover_2016.jpg Portfolio - Synthetic Molecular 8-19 Knot Molecular strands braided into a 20 nm continuous loop with eight crossings. 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