Biocinematics

Tying Different Knots from One Molecule

Biocinematics_tying_different_knots_cover_2020.jpg

Copyright

© 2020 David Leigh

Description

A sculptural representation of a molecule being tied into two different knots, a trefoil knot on the left, and a five-crossing knot on the right. This process occurs by the molecular strand binding first to either a lutetium or copper ion, or both, at specific binding sites. The order of metal binding at these sites (represented with copper and silvery metal regions in the illustration) determines which knot conformation is formed.

Featured Research

Leigh, D.A., Schaufelberger, F., Pirvu, L. et al. Tying different knots in a molecular strand. Nature 584, 562–568 (2020). https://doi.org/10.1038/s41586-020-2614-0

More information

http://www.catenane.net/pages/2020_molecular_5_2_knot.html


Early concept of the proposed journal cover

Early concept of the proposed journal cover

Five-crossing knot tying

Five-crossing knot tying

Trefoil knot tying

Trefoil knot tying